Analysis of the modified rankin scale in randomised controlled trials in acute stroke: a systematic review
نویسندگان
چکیده
منابع مشابه
Analysis of the modified rankin scale in randomised controlled trials in acute stroke: a systematic review
Background Historically, trials in acute stroke have largely been unable to show benefit of new interventions. Trials have previously favoured dichotomous analysis of outcome measures employing an ordinal scale, such as the Modified Rankin Scale (mRS). In 2007, the OAST Collaboration showed that preserving the ordinal nature of these scales increased statistical power, recommending the use of o...
متن کاملAnalysis of the Modified Rankin Scale in Randomised Controlled Trials of Acute Ischaemic Stroke: A Systematic Review.
Background. Historically, most acute stroke clinical trials were neutral statistically, with trials typically dichotomising ordinal scales, such as the modified Rankin Scale. Studies published before 2007 have shown that preserving the ordinal nature of these scales increased statistical power. A systematic review of trials published since 2007 was conducted to reevaluate statistical methods us...
متن کاملUse of the Barthel index and modified Rankin scale in acute stroke trials.
BACKGROUND AND PURPOSE The Barthel Index (BI) and the Modified Rankin Scale (MRS) are commonly used scales that measure disability or dependence in activities of daily living in stroke victims. The objective of this study was to investigate how these scales were used and interpreted in acute stroke trials. METHODS We identified from MEDLINE the major efficacy trials with neuroprotective drugs...
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BACKGROUND AND PURPOSE A perceived weakness of the modified Rankin Scale is potential for interobserver variability. We undertook a systematic review of modified Rankin Scale reliability studies. METHODS Two researchers independently reviewed the literature. Crossdisciplinary electronic databases were interrogated using the following key words: Stroke*; Cerebrovasc*; Modified Rankin*; Rankin ...
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اندیشمندان و صاحب نظران علوم اجتماعی بر این باورند که مرحله تازه ای در تاریخ جوامع بشری اغاز شده است. ویژگیهای این جامعه نو را می توان پدیده هایی از جمله اقتصاد اطلاعاتی جهانی ، هندسه متغیر شبکه ای، فرهنگ مجاز واقعی ، توسعه حیرت انگیز فناوری های دیجیتال، خدمات پیوسته و نیز فشردگی زمان و مکان برشمرد. از سوی دیگر قدرت به عنوان موضوع اصلی علم سیاست جایگاه مهمی در روابط انسانی دارد، قدرت و بازتولید...
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ژورنال
عنوان ژورنال: Trials
سال: 2015
ISSN: 1745-6215
DOI: 10.1186/1745-6215-16-s2-p130